Norepinephrine Drip Rate Calculator
Titrate levophed precisely — enter dose in mcg/kg/min and patient weight to get the mL/hr pump rate for your norepinephrine bag. Supports 4 mg/250 mL, 8 mg/250 mL, and custom concentrations.
Norepinephrine quick reference
| Dose (mcg/kg/min) | Clinical target |
|---|---|
| 0.01–0.1 | Low — MAP support, septic shock start |
| 0.1–0.5 | Moderate — refractory hypotension |
| >0.5 | High — consider second pressor |
Ranges are general ICU references. Titrate to MAP target per your institution's sepsis protocol.
Formula
For standard 4 mg in 250 mL bag: concentration = 16 mcg/mL. For standard 8 mg in 250 mL bag: concentration = 32 mcg/mL.
Frequently asked questions
What is levophed's standard concentration?
4 mg in 250 mL D5W gives 16 mcg/mL. Double-strength (8 mg/250 mL = 32 mcg/mL) is common in fluid-restricted ICU patients.
How often do I titrate norepinephrine?
Typically every 5–15 minutes per MAP response in septic shock (Surviving Sepsis Campaign). Adjust to maintain target MAP ≥65 mmHg.
Can I use this for post-cardiac surgery patients?
Yes. Enter the concentration your cardiac surgery unit uses — the formula is the same regardless of indication.